SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b26e192545471347c4ece9b2cd62278c7b3c5c64c47285dd5c3a88d9a7df3edb' 
  AND token = 'NzQC4nb78W3YLrQOfAdPwq2u+nkRNHPdFF9dm0oaAuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}