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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b05e9d86933a28b2db4daeac479c9bc910b060cb4a0a22e7a0ca2e79bad0368' 
  AND token = 'RGO1FwApp7oF5U/mNIOlp01CYL2su5b+46i9GIoYf3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}