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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a05f9e90922f3a34b30295c0c5ab391cd9d440e109fdb04db88c4362b3018a10' 
  AND token = 'UktOGryzzo5kG8s2gnZoBBC5DcIXHT43AjuUa987vd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}