SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '196bcb9f24f10eeef1c44010f24c26155c5ce60c7288e68d80c384cdcc053cce' 
  AND token = 'YNZSyL21KNK/VcUUlcxHHdFBEdMfRgE2fkxHpLwDdP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}