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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a95f57589fdbd1a484c13f66396f03c511c5c6cef1d1e0611f2e094b83b65de' 
  AND token = '0xvyrhOkMz1eHAYY9nfjcJ6+k/JuLiClSCZcfX9jmIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}