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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de729e40e60797d71d1f0a5515d1f27a861c93c59e48a7b8e19acd43975d34ee' 
  AND token = 'iE1s6GfZ4+fOMIUWhU3mUMx7XcroIKEZ+Wl1C/Z1MHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}