SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d95fdbfc2e7de775973c70ed4d360b9fb260f18f9f6615b0e61095bba1e63f0' 
  AND token = 'NRtSxj2rjF38edXytxmN/0Lec6nd6o6ovamMNARFIBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}