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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0027411aa0e4dbbae76abf7e19bec00d1b7fa1f675dddc02b4d62e225b660eba' 
  AND token = 'hs2iby8LFsfjCGf5GjMAIzx3UB0tWTvFOD0Nbr99Xxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}