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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c356668cd5b9b3c546fa480d3cdb1d9628a1edab4560893d094e8352a14861d' 
  AND token = 'YtzMjMMfmV82NDrHcLhvIdVQWHHipJ91SOzbaQ3sAsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}