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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bef2fe853e4c4c57e733992b76b2b21daf0551633ffe3161e6733e7dda8c724c' 
  AND token = 'dxjIQhHJwssIwmJacf1AXCCXa3dD9hCxPz+WtqlTpMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}