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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a217b444fe440313ef9635d3d641747629aa4f88551087b99c53574530e67e0' 
  AND token = 'EfA5BpzsbcW6x/out+2Nm4eZhtlhcEs25uoLzXrfz+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}