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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8106fa65c6c8428dfee9ced17b22b98ec9453bc0311e2d8d485216e6e1e8b33d' 
  AND token = 'hk+ebrtdURalsVPYf/m5WEXCAk83wA1gV2YBw9TSQlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}