SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fdeed86787e173b02aa34cba96048ded87a56fa1ac7edb2fd5dae6b587a8dea' 
  AND token = 'VxcAnY/0hm253SRgTf7ZvfEx/ki0GpVOYG2teMJ8MdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}