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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b6125ce6f989b2eb5e62a6c49019db0f20cd40397d3533da8da3706403d846b' 
  AND token = 'dyBRdxzvs5YaW8LesM4MZULD2phmS3mR2QsSmCy6hyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}