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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06cb5f917277c42b7a4a6633fb2fc694b03cf2bf27be69d6b97761044a61395b' 
  AND token = '4KLAuIjuFxzM+J4nruqVkY3Y5t+SBZqlAkSsSr9eejQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}