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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c98e1e05825d40b5a4407283d07020fa8a052be7a880ab678c6e4befb4280ecb' 
  AND token = 'zxs0TQjGWyIO0R9Is/6rmR3hUHdnohTDo1++aTGS2kg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}