SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e3dcad205371dbae46993e9a02a5f0b046ffd9d31d5c6c5237e13f601b3dccd' 
  AND token = 'SkHtjK1wUp0IvzfdqksWj4PDP3HGw/UlRgX9pvfJujo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}