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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd5b749b63d0308e1821b56a0572926186e34f8581329f0a4005f8b49d75fef9' 
  AND token = '7ratBkFheclXG3mkpXcQIURjfAP3nE3OctKEWWvnMWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}