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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5c5ab63057e2b6945700307bfb8990e7383e0056c4d01ce74e4f69478bf140f' 
  AND token = 'cW/zYC4Nj2OsIOQKdMSmCX7xM+FSNcXvDZuL8e5HeRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}