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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52535c3fd316ad2c464c2710d96fdd237b2b79a3425e8de9c57c8d8c7a01dc65' 
  AND token = 'gVfqqNDU2XQWkH5xIRuSo/pFmf0nr0SMn6FAb2lz+io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}