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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbdc4568d11192a2d75f6f5959f85f35ca9c9e34a99d11149fae81e729b83925' 
  AND token = 'zUlaKkQdm61KyPWTTdOXiVYzBbbOAscY79obiaavEGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}