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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4803fbbfa072afc763cedc70bc11454f7aa3c8c222eb1a185679f29345bd57e1' 
  AND token = 'AdYB3/0arnz4/YyfffyXNboiZMsbF1X2Ewf/XWIzTXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}