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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32c0c7b97cb612cf180508f161012afe382aaad5711a8c16c1590d102f2a8fa2' 
  AND token = 'UgKdzOkhtmubi+28GSVbrW4mtafgpwprnT3L8qwPggs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}