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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c35b36e1a5cd3aaa653e0653fabd54e9bafa9b44df7af9b428777be1a424142' 
  AND token = 'ktS+51lt/vFvw+64GVkKA3l7k+OWdpU5zF5ZNXzHl/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}