SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '035fa0f1b64f68f389a651966f2510808a020e6376069ed427e740d6ac4a3ba4' 
  AND token = 'HcCcipUqJYEfh1FhUfrb6rvalZz3jQFCrwZpzR2aDAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}