SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dd6b5dc8bf12a18f45b718a0e6d97c8779a1d833fef9266a93046b5b13f9037' 
  AND token = 'M2KgM2LbpX+kHanAk/RPMtAOSwskvkAPrmtf77yUFZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}