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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a59ded26f8c5ec2eac8508ae510ece228b96a92c102af92f44281ce45d4ccc2b' 
  AND token = '+c8tuUj6UD7NynHbAf+qmLs/zqDhoktArCXh31MDUyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}