SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0214c1eaca8fae1ec5aba0bab549d7b8daed2186f56b5ea2c885b5664cc572c' 
  AND token = '6HDAP181FX6VvK23pd/5UbAUgnsYMbDuleJBiLWgURE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}