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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4bc3f8813fd2f984c181092278e176faa1fcb97ecb5f870790a1ab283e3ad45' 
  AND token = 'OvLTp/sNjssU9WsXIKk4WuP8zd8uoI/pdrDgDQUzhCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}