SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae86e88775b0d2c2c3da6d2d40fad090a8c4b511da4d6ce9938095ae2238dabf' 
  AND token = 'PV/2FPzlMOsGM19p+grzzlrnX/dM8s136ZRzPr3BzKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}