SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ee1e8b36a8a051d025540b2f36eae1a2c6178879529da19b1194ec580769f1b' 
  AND token = 'lWdAxDQCmrZKqUtAhLLL/TUDVWaHs/0truDnmqJo0ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}