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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d5eb837536d91cde96c3c832f3921faf3e34d15070fac754c0f2ce6bb02d06c' 
  AND token = 'Xs1Qi+aYH7D8fQhNFvPBwmR6S14Q5GFCYQasC2salFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}