SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cda367c4d355f3dd28d3b6991ea101902a56c4c82e6a7968b95c0b86d6e0aa7' 
  AND token = 'IguDvjEWsrFGti/rpMMu+eoMTKMwkYYOtZiH5nVoPuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}