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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '925c18a7879a235c0b9e433878f87695f3646eb0a130861405d0105de63e554a' 
  AND token = '6IGfvaPdjzTb4fWWcfgUViV6uBr+OzI1XfaPdjZRGTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}