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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2297e588ede95e5f4077b3a2e4543940ce0f00dda3e3c2a7574580a8c028a9a' 
  AND token = 'fm+CJClNDEfqBiCBW7JVJqZXbWGNVxEgG8uSM4OtlYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00072

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}