SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54858f0809783b91d6aa2be8d0514c96a02be8012b6bbd521d67c905d2534897' 
  AND token = 'dcCElSE/y9SN+N4/TrKyGQ1vLlzHboywv3XxEPvOMZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}