SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fde4f6e74f160af0e92df046f8e337e25c134d4eb00a152e056404d281c2ecd' 
  AND token = 'PdFHnhsF/z53DcUDcZvH5svVbJbH/tzj67dK4W5x74c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}