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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cbc16a6374e86cfb4816afb216e38079a4c65ba8c9c64a3ee08b4426a578326' 
  AND token = 'c/SG+uTc2kukYBkD7B+K4b4qRhCnvzHlyJnQLbd2TeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}