SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be47b2674ff9a7f66e40f058e916a4db806b8729e911686c52168aef401722b6' 
  AND token = 'W+8XZwGMR8Q6k+MsKbcZRHj9xWiUmZRJ4MRTGtbCSYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}