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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7228f1c03c8f1ee8c69cbeff460ee06f741c7d04b65735958180ccfa81b522ce' 
  AND token = '7Z7+4UetRQKbwoBDBsLTYOTc7YKA7Q0pXYhp0YDaR2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}