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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75437cd99e6702cf957b916361c3cc5a6c6c77eccf5bb1127bf53719f2b8444a' 
  AND token = 'CQCnNufsx3DzQ+l/ibuRyZQds/+qs3gv8lQdGpaqZWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}