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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a9539d4a77736fb86ca2c64a3d690f1f8bdd15a7c5c09865dee275e3287f5a5' 
  AND token = 'P+sHSc5rOM2suf/IrictJmpLcbjhMNBWy3xDj82/Ic0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}