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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b26383f2931c314050a17c34de3aa0ca77a75eb739d3676ba48bf6974e08400' 
  AND token = 'zK9AqB5FLEYox+FL4HEA3dA/itfM8MjVxxA/Ha46FX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}