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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7de0088f598eddee0c92b218c42ae3362fe74951dedff3f8a84bccc6771b9b02' 
  AND token = 'Ux41ERDXj8vnQUY+888SyJDvwc4HdEoT9+Y2ADF0F3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}