SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b82819ebea11a5fef73d0e444092fd683e31ffe013dd42168afb344d5659f08b' 
  AND token = 'cS6zzicAr0NGOM3LIMFVvIUp7eyLLBvCiw6iB/wNNgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}