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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05a078077db0a641796151eae935c810e760780171472784171090c7e22ba835' 
  AND token = '2akmrWOciUZ09Jg0V3/zqIy5blVcvLCSDUSDrVy0sXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}