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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb82505c7988b6c4a183ccc1a1e9289d6a2109b04952056d74df1b86b4c8d94d' 
  AND token = 'cM29JlAjwLA9jXIgMH04mHM+gMOoP26BgIgjR0bFVF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}