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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2de66d78697ce069ff3cc0c1508a14f7a9bc582fa33137f2846f5e9ea799545' 
  AND token = 'eMNqL6gBcjX0lljHcsjbxZRVsNxdwDlosLbWkc91zeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}