SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1544afe9aee365b31adc0a323b52a99a5b627b71bee29e17940c11605a41ce5d' 
  AND token = 'Sb88/5nWRmzF9eHAwK9FDu55RUEh3nUxY4JnkZUOdOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}