SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4d17d4450415cc669dfa1c9c2b340797de9a7208c2494a59b638451cbe22443' 
  AND token = 'EBylvR/RpzT0W2FJeXVwzdCdIHWF9MuE4iezoIKNc1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}